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Gough CE, Sharpe K, Garvican LA, et al

Previous studies performed conditional FBXL5 deletion in specific cell types and demonstrated that FBXL5 deficiency increases the cellular iron levels, primarily due to the abnormal accumulation of IRP2 in vivo 18,19,20

Key issues include ensuring informed consent, balancing maternal autonomy with fetal welfare, considering the implications for family planning, and ensuring equitable access to diagnostic services