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Teste de independncia de vias de sinalizao do receptor em modelos genticos Estudos pr-clnicos utilizaram modelos genticos de camundongos (incluindo modelos com deleo do receptor 3-adrenrgico) para avaliar se os resultados relacionados ao metabolismo lipdico observados com o AOD9604 so mantidos na ausncia de componentes especficos da sinalizao adrenrgica

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[DOI] [Google Scholar] 30.Meiners S., Eickelberg O

Of the two arms, one is designed to provide tumor specificity, while the other has the role of triggering the signaling potential