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Effects of L-carnitine against oxidative stress in human hepatocytes: involvement of peroxisome proliferator-activated receptor alpha

The local production of apoE is likely a critical atheroprotective mechanism considering that areas of atherosclerotic lesions have limited accessibility to plasma apoA-1 and HDL (100,101,125)

The results of the above animal experimental studies proved the positive effect of vitamin E, which prompted more researchers to seek its effectiveness in clinical trials