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10.1016/j.tifs.2020.10.024 231 SumitG.SubudhiE.NayakS

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Cyclosporine A, traditionally an immunosuppressant, at low doses blocks the mPTP

Despite the availability of many antihypertensive medications, several hypertensive individuals are resistant to standard treatments, and are unable to control their blood pressure

If this system is disrupted, such as by selective small-molecule inhibitors, like iFSP1, or by gene deletion, the loss of FSP1 function promotes ferroptosis