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The bioavailability was limited and was 7.78% in rats

10.3389/fonc.2024.1384928 133

Also, DFX can alleviate the lipid peroxidation and endothelial dysfunction in MAECs, inhibiting the occurrence of ferroptosis, and then improving AS lesion ( 4.4 Radical-Trapping Antioxidants RTAs, reacts with chain-carrying peroxyl radicals to produce non-reactive free radicals (Li and Pratt 2015), which destroys the autoxidation of chain-propagating peroxyl radicals (Kajarabille and Latunde-Dada 2019)