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Although the non-parenchymal cells can be isolated from the 50 g supernatant, the yields are usually low

Lusardi, T

M.DaminkS

3) is another TLR family member upregulated in MASLD and lipopolysaccharide (LPS), ROS, HMGB1 and various damage-associated molecular patterns can bind to TLR4 in KCs to promote TNF-, IL-1, IL-6 and interferon- (IFN-) production of various pro-inflammatory cytokines, thereby contributing to hepatic inflammation and the progression of MASLD (54)