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Moreover, an excess of fatty acids and lipotoxicity predisposes to inflammation and type 2 diabetes mellitus, inducing macrophage iron accumulation via FTH1 gene activation, which encodes the ferritin H subunit [35,36]

Prevalence of dampness and mold in European housing stock

Structurally, ALA contains a redox-active disulfide ring that can be reversibly reduced to dihydrolipoic acid (DHLA), forming a powerful intracellular redox couple

Malaria infection induced anti-tumoral effects via triggering a strong immune response, releasing IFN- and TNF-, and the activation of NK cells

This relationship enabled prediction of lipid disposition without extensive in vivo screening, providing a practical framework for lipid design