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Under normal physiological conditions, the C- and N-termini maintain the interactional state to inhibit the cell membrane perforation function of the N-terminal domain

& Gumbiner, B

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Ascaris primary siRNAs Several studies suggest that the introduction of dsRNA leads to RNA interference in Ascaris embryos (Davis, R.E., unpublished), larvae 103,104 , the isolated and perfused adult intestine 105 , and muscle 106 through injection of dsRNA into the pseudocoelom of adults