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The primary endpoint was the global cognitive and functional scale, Clinical Dementia Rating Sum of Boxes (CDR-SB)

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Unlike other regions where supplements might be imported or sourced from overseas with different regulatory standards, Australia has specific guidelines for supplement quality, meaning local brands often prioritize transparency, effective formulations, and adherence to these strict health guidelines

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Overall, this strategy has been very successful, but not all patients respond, responses can diminish over time and numerous side effects can occur