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Moreover, liver pathology was assessed, and immunohistochemistry staining was conducted for activated macrophages as an indirect measurement of inflammation

Following a one-week acclimatization phase, experimental procedures were conducted in accordance with international animal care and ethical guidelines, approved by Cairo Universitys local committee on animal care and use (CU/I/F/28/19), and reported in accordance with ARRIVE guidelines

Mitochondria (Organelle Source of ROS) The mitochondria are the primary intracellular generator of ROS

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Additionally, NDGA enhances H 2 O 2 sensitivity and increases Mtz sensitivity in H