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Selumetinib in children with inoperable plexiform neurofibromas

Major Ingredients Water (Aqua), Butylene Glycol, Alcohol Denat., Niacinamide, Sodium Hyaluronate, Glutathione (20ppm), Morus Alba Bark Extract, Glycyrrhiza Glabra (Licorice) Root Extract, 1,2-Hexanediol, Lilium Tigrinum Extract, Jasmium Officinale (Jasmine) Flower Extract, Nelumbo Nucifera Flower Extract, Adenosine, Hydroxypropyl Cyclodextrin, Phenyl Trimethicone, Disodium EDTA, PEG-60 Hydrolyzed Castor Oil, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Ethylhexylglycerin, Phenoxyethanol, Fragrance (Parfum) Ingredients subject to change at manufacturer's discretion

Most importantly, the procognitive/antidementia capacity of orally delivered dihexa was blocked by an intracerebroventricularly delivered HGF antagonist, as measured using the Morris water maze task of spatial learning

After a 7-days acclimatization period, the mice were randomly assigned to five groups ( n = 8 per group), Normal Control (NC) group: did not undergo modeling induction

Additional details regarding the laboratory analyses can be found in Kitowski et al