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41 Many factors that normally stimulate ET-1 synthesis, (for example, thrombin and AT-II) also cause the release of vasodilators, such as prostacyclin (PGI 2 ) and/or NO, which oppose the vasoconstricting function of ET-1

While plant-based sources of B12 exist, studies have shown they are poorly absorbed and have little to no effect on our B12 blood levels

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Food and Drug Administration (FDA) for medical use in humans