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ANIT is a hepatotoxicant that induces portal edema, parenchymal necrosis, and inflammation of the bile duct epithelium

any infusion should have immediate access to emergency care

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Nat Immunol 18:374384 Visser K, van der Heijde D (2009) Optimal dosage and route of administration of methotrexate in rheumatoid arthritis: a systematic review of the literature