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Variations in oxidative susceptibility among six low density lipoprotein subfractions of differing density and particle size

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397 In a Phase II trial (NCT02420314) for advanced NSCLC, Ascorbate combined with Carboplatin and Paclitaxel inhibited tumor growth through HO generation, iron modulation (higher transferrin linked to improved PFS), and immune activation (4.2-fold increase in CD8 + T cells), achieving a 34.2% response rate and a 12.8-month median OS