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48 Furthermore, research from 1997 found that, in healthy men, folic acid supplementation reduced homocysteine levels in all tertiles except the lowest tertile, in which average baseline levels of homocysteine were 7.07 mol/L

Therefore, the mutation of the Y296 residue slows flavin reduction and, in terms of rate, delineates this from the binding of NADPH

These modifications enhance the structural and functional diversity of the proteome via the covalent attachment of functional groups, proteolytic cleavage, or the degradation of entire proteins

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Adv, 2015, 33, 666680