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This pigmentation occurs most often on mucous membranes or modified mucous membranes, but it can also arise on keratinizing skin

[DOI] [PubMed] [Google Scholar] 199.Thornalley P.J., Langborg A., Minhas H.S

Prx3 homodimer has a redox-sensitive cysteine that upon reaction with H 2 O 2 is oxidized to Cys-SOH, which then reacts with neighboring Cys-SH of the other subunit to form an intermolecular disulfide that can be readily reduced by thioredoxin reductase 2 (TrxRD2

Stimulating melanocyte activity while simultaneously making it harder to visually distinguish normal mole changes from dangerous ones creates a genuine monitoring challenge