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Efficacy and safety of extended- versus immediate-release pramipexole in Japanese patients with advanced and L-dopa-undertreated Parkinson disease: a double-blind, randomized trial

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We advocate that the following clinical characteristics may provide important signs for clinicians that LS-related EC should be suspected with a diagnosis of EC: (1) Patients, particularly with pathologic diagnosis as endometrioid carcinoma, show no evidence of estrogen overstimulation such as low body mass index (no obesity), no history of polycystic ovarian syndrome, nor unopposed estrogen usage

However, the true advancement came when researchers combined it with a potent compound your body doesnt produce: 5-Amino-1MQ