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doi: 10.1126/sciimmunol.abf6692 154

doi: 10.1074/jbc.TM117.000259 184 SongX.ZhuS.XieY.LiuJ.SunL.ZengD.et al

For instance, 5-HT is a neurotransmitter associated with mood and behavioral inhibition, and elevated levels can lead to increased feelings of fatigue, a phenomenon known as the central fatigue hypothesis. As shown in Figure 1b, 5-HT in the brain is metabolized from tryptophan through tryptophanase (TYH)