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Defective regulation of the ubiquitin/proteasome system in the hypothalamus of obese male mice

Psychiatry 24 , 776794 (2019)

Induced rodent models, while useful, exhibit varying degrees of reproducibility and inconsistencies in the extent of RGC damage they produce (101)

26 More importantly, unlike caloric restriction, LCA does not induce the adverse effect of muscle loss observed in caloric restriction, offering a superior strategy to enhance healthspan