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The second microsomal enzyme is a hemoprotein called cytochrome P450, which serves as the terminal oxidase

Pro-Oxidant Potential: In certain conditions, such as in the presence of metal ions or high concentrations, ascorbic acid can become a pro-oxidant, generating free radicals that may damage skin cells instead of protecting them

Interleukin-1 also happens to be upregulated in fibroid tissue, thus decreasing the tumor suppressor.[ref] Exposure to endocrine disruptors Adding fuel to the fibroid fire, exposure to endocrine-disrupting chemicals such as BPA and phthalates also increases the risk and growth of fibroids

[6] Exceptions exist when elimination is extremely rapid: for very short-acting agents, the phase can meaningfully shorten effect duration even after a single dose (e.g., triazolam, midazolam)

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