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Mechanistically, ammonium disrupts acidic compartments, as indicated by reduced LysoTracker staining, likely impairing the pH-dependent maturation of perforin (79)

In the kidney, the level of N -(carboxymethyl)lysine was significantly lower in the mice fed a lard-based diet

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this thermal energy activates TRPV1 and TRPA1 expressed in the surviving functional cones, and the response extends to the GCL of the Rd1 retina, a result similar to that obtained in the wild-type (Nelidova et al., 2020)