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It is found that miR-20a-5p could reduce the kidney loss and structural damage by inhibiting ACSL4-dependent ferroptosis [112]

This impairment was evidence both when glucose was the primary fuel source, and when fatty acids were used alongside the uncoupler carbonyl-p-trifluoromethoxyphenylhydrazone, which bypasses the respiratory control mechanisms

Tolerability, preliminary efficacy and pharmacokinetic of CC-223 was evaluated in a daily dose

Therefore, there remains an unmet need for additional approaches to alleviate sputum symptoms in COPD patients