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The main causes of vitamin B12 deficiency are Autoimmune disorders, Low dietary consumption, and Malabsorption

Common clinical drivers include: Vitamin B12 deficiency Folate deficiency Chronic liver disease Alcohol use disorder Medications (e.g., methotrexate) Bone marrow disorders Chronic inflammatory disease Hypothyroidism Key ICD-10 principle: Cell size is a laboratory observation

Do not shake the mixture vigorously, or the molecules will get destroyed on the spot

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A review of 18 different studies in patients with NCGS found iron deficiency was present in 15-34% of patients