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In contrast, advanced HCC patients are typically treated with transarterial chemoembolization (TACE) in combination with targeted therapies [1]

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Interdiscip Toxicol 2015;8:5564

Low levels of FLNA, causing loss of coupling of SSTR2 with downstream signal transduction molecules, might explain the resistance to SS analogs in GH-secreting pituitary tumors even if in the presence of SSTR2