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(2006) and Holve (2007) as follows: (Holve et al

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Clinically, this resistance manifests in two distinct patterns, arising from both the progressive functional exhaustion of tumor-specific T cells and the dynamic equilibrium between immune attack and tumor evasion, which are continuously challenged within an immunosuppressive tumor microenvironment (TME) sculpted by immunoediting

To further probe the catalytic mechanism of arGSTs, we conducted quantum mechanics/molecular mechanics (QM/MM) calculations based on the ternary complex of GSH, ()-catechin ( 12 ) and Pt GSTF8

10.1016/S0022-510X(96)00203-1 J