The market is expected to achieve a compound annual growth rate (CAGR) of approximately 8.5% through 2035, with the market index (2025=100) reaching 215 by the end of the forecast period
Disclosures: Jae Seung Lee: Nothing to Disclose, Sung Won Lee: Nothing to Disclose, Sang Gyune Kim: Nothing to Disclose, Yeon Seok Seo: Nothing to Disclose, Su Jong Yu: Nothing to Disclose, Hyung Joon Yim: Nothing to Disclose, Hye Won Lee: Nothing to Disclose, Mi Na Kim: Nothing to Disclose, Beom Kyung Kim: Nothing to Disclose, Jun Yong Park: Nothing to Disclose, Do Young Kim: Nothing to Disclose, Sang Hoon Ahn: Nothing to Disclose, Seung Up Kim: Nothing to Disclose 407 FUNCTIONAL ANALYSIS OF FUMARYLACETOACETATE HYDROLASE AS A HEPATOCYTE HOST FACTOR GENE REGULATING HEPATITIS B VIRUS REPLICATION AND HEPATOCARCINOGENESIS Shouichi Namikawa 1 Takuto Nosaka 1 Yosuke Murata 1 Tomoko Tanaka 1 Yu Akazawa 1 Kazuto Takahashi 1 Tatsushi Naito 1 Masahiro Ohtani 1 Yasunari Nakamoto 1 , 1 University of Fukui Background: Recent molecular biological analyses have highlighted the importance of host factors in anti-viral and/or anti-tumor effects
Crucially, we integrate the parallel and essential discourse on safety, highlighting how zebrafish models, especially transgenic lines, enable the real-time visualization and mechanistic interrogation of compound-induced hepatotoxicity
doi: 10.1016/j.matlet.2015.06.118
Certain drugs are inactivated so efficiently upon their first pass through the liver that they cannot be administered orally and must be given parenterally
