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Reactive oxygen species/photothermal therapy dual-triggered biomimetic gold nanocages nanoplatform for combination cancer therapy via ferroptosis and tumor-associated macrophage repolarization mechanism

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Eventually, a buildup of oxidative stress can cause permanent damage and may lead to things like heart disease and cancer.74 Antioxidants have free electrons that they donate to those oxygen molecules, taming them and allowing the body to repair damage.74 There are thousands of antioxidant compounds, but things like omega-3 fatty acids, vitamins C and E, polyphenols, and carotenoids are potent antioxidants

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Kla provided the first evidence that lactate directly modifies histones, leading to transcriptional changes in macrophages and regulating the cellular transcriptome