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doi:10.1016/j.freeradbiomed.2023.04.024 Alehagen U, Aaseth J, Lindahl TL, Larsson A, Alexander J

Yang S, Wang XQ

The main goal of 3D cultures is to provide cells with a bulk ECM with properties that guide cells to develop or sustain a desired phenotype and, implicitly, to rely upon the cells themselves to create a local 3D microenvironment that mimics the in vivo microenvironment

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By comparing an AGE-directed strategy with antioxidant repletion, this study aims to clarify whether targeting AGE-related molecular damage provides benefit beyond general redox support in the context of diet-associated reproductive dysfunction