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Additionally, the NNMT substrate nicotinamide 12 is metabolized by the microbiome 56,57 , and thus NNMTi may modulate substrate availability, potentially influencing microbial metabolic capacity to drive the NNMTi-mediated weight loss

Even though its unlikely to cause serious toxicity or injury, you have to ask yourself if its worth it to put this form of B12 into your body knowing that it must be eliminated and detoxified

10.1007/s00125-014-3490-7 66 KanntA.RajagopalS.KadnurS

These shots are typically quick and easy to administer, and they can benefit individuals who have difficulty absorbing B12 from food or supplements

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