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These complex sugars can then be transferred to lipids and proteins or used for metabolic or structural purposes

It has been suggested that activation of the SSP is important not only for serine production, but can also contribute to the generation of -ketoglutarate (through the PSAT1 reaction) 14 or the redox balance in the cell (as PHGDH consumes NAD + ) 40

Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing

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Other constituents of tobacco smoke, such as carbon monoxide, along with oxidative stress, appear to play additional roles