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All methods were carried out according to the relevant guidelines and regulations

Additionally, this group demonstrated significant decreases in blood cadmium levels and in the following enzymes: alkaline phosphatase, alanine aminotransferase, and aspartate aminotransferase

Treatment with N-acetylcysteine partially rescued the tumor-promoting effects driven by NRF2 in FN3K-deficient models, underscoring the importance of NRF2-mediated redox homeostasis [138,139,140]

It has been reported that when ferroptosis occurs in neurons, then microglia are activated and release toxic substances including pro-inflammatory factor IL-6, which can cause neuro-inflammation and lead to further brain damage (Tang et al., 2020)