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Folate, in the form of methylenetetrahydrofolate, is a necessary substrate for the conversion of uridylate to thymidylate and the subsequent incorporation of thymidine into DNA

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PLS-DA models with corresponding values of predictive power (Q 2 ) higher than 0.50 were considered statistically robust

However, it is less effective for treating retinal conditions, primarily due to rapid clearance of drugs from the ocular surface, non-targeted delivery, and the distance between the ocular surface and retina, contributing to a low drug bioavailability in the posterior segment [41]

Genome-wide exploration of the drug action of capreomycin on Mycobacterium tuberculosis using Affymetrix oligonucleotide GeneChips