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Some clinicians use TA1 offlabel to support patients with autoimmune disease, citing its ability to modulate the immune system without broad suppression

Interestingly, salt-induced TZF1-GFP foci appeared to be more abundant at 24 h in TZF1 H186Y OE plants than TZF1 OE plants, suggesting that TZF1 H186Y -GFP protein might be more stable, albeit non-functional, in salt stress tolerance

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To identify effective PI3K-mTOR inhibitors with favorable PK profiles for NF1 -mutant patients, we screened eight dual inhibitors using normal intestinal and liver organoids (Supplementary Fig