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Co-crystal structure of 7b in complex with KRAS G13C mutant To further characterize the novel nucleotides with the cyclic linkers, KRAS G13C was co-crystallized with compound 7b to obtain detailed structural insights into ligand binding within the binding pocket (resolution:1.85 , R work : 18.98, R free : 22.78

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TrivediVSMagnusenAFRaniRMarsiliLSlavotinekAMProwsDRet alTargeting the complementsphingolipid system in COVID-19 and Gaucher diseases: evidence for a new treatment strategy

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Researchers Rahmati and colleagues found that administering probiotics to mice with cerebral hypo-perfusion improved spatial memory and reduced neuronal damage in the hippocampus [198]

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Nat Rev Neurosci 2015;16:64759

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