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Niacinamide (vitamin B3) supports NAD+ production, which is involved in cellular energy metabolism and DNA repair

10.1200/jco.2011.29.15_suppl.5592 J

Oxidative Medicine and Cellular Longevity 2012:324832. [doi.org]

3.3.4 MGBA alterations and pathophysiological mechanisms in anxiety Rodent models of anxiety disorders provide causal evidence that stress exposure disrupts the MGBA, leading to microbiota alterations, compromised gut barrier integrity, immune activation and neurotransmitter imbalance (Bear et al., 2021)