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Importantly, the beneficial effects of metformin have been confirmed via a post-hoc pooled analysis, demonstrating its potential in improving SLE disease activity and decreasing flare risks, particularly in serologically quiescent SLE patients (171)

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The ASQ-3 is an easily administered checklist of developmental status standardised for children aged 166 months.35 The screening system includes age-appropriate questionnaires for every 2/3-month intervals