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Hereditary cerebral folate malabsorption is a secondary cause of cerebral folate malabsorption, with nearly half of the patients having a consanguineous parent and a mortality rate of 40%, with women being more susceptible than men [114]

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4 It is characterized by distinct morphological features, including cell contraction, chromatin coagulation, DNA fragmentation and apoptotic body formation

These two types of estrogen receptors are expressed with tissue- and cell-specific deliveries