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The largest contributors to the list of potential drug targets in this study were proteins (9 out of 25) involved in the LPS biosynthesis pathway (Sarkar et al

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Evidence for mitochondrial uptake of glutathione by dicarboxylate and 2-oxoglutarate carriers

This nephropathy originates from diabetes-induced dysregulation of glucose metabolism, which in turn triggers a series of metabolic abnormalities, hemodynamic changes, inflammatory responses, and fibrotic processes that ultimately drive disease progression (Tuttle et al., 2022)

The second antigen, small nuclear ribonuclear polypeptide A, also known as U-1A, is a 70-kD peptide recognized by anti-ribonuclear protein autoantibodies associated with mixed connective tissue diseases (i.e., arthralgias, Raynauds phenomenon, arthritis, myositis, pulmonary fibrosis, and sclerodactyly [71, 72]