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It is reported that the hyperacetylation modification of mitochondrial proteins caused by the imbalance of NAD + redox mainly promotes the pathological remodeling of the heart through two different mechanisms

2004 Jan;49(1):737

Multinational clinical study comparing isatuximab, carfilzomib and dexamethasone to carfilzomib and dexamethasone in relapse and/or refractory multiple myeloma patients (IKEMA)