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It is involved in the pathogenesis and progression of lung diseases such as Chronic obstructive pulmonary disease (COPD), asthma, and idiopathic pulmonary fibrosis, prevents the spread of pathogens in the body, and regulates the composition and function of gut microbiota

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Remember that peptide research and application continue to evolve

The underlying mechanisms by which autoantibodies and IFN- promote CREM nuclear translocation remains unknown

FMT experiments further demonstrated that gut microbial dysbiosis enhances the intestinal permeability in microbiota-depleted mice and mediates intrarenal activation of NOD-like receptor signaling [135]