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Its melanin-inhibiting effects can also reduce hyperpigmentation

Macrophages were also found to be required for angiogenesis in xenografts secreting VEGFA or overexpressing zebrafish VEGFAA, suggesting that zebrafish macrophages enhance VEGFA-driven tumor angiogenesis

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Studies have also shown that epigenetic modifications, such as DNA methylation and histone acetylation, can modulate the expression of stress-responsive genes and enhance plant stress tolerance (Jaleel et al., 2007

Interestingly, eliminating phase separationby either mutating the acidic-type TAD or substituting basic residues in the DNA-binding motifbarely impairs PIF4s ability to restore warm temperature-induced hypocotyl elongation in the pif4 mutant