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SPSB1 binds to TRII, resulting in its ubiquitination and destabilization, thus suppressing the TRII-Akt-myogenin signaling pathway and compromising protein synthesis within muscle cells

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With a meal : some choose to take it with food for better absorption

FIGURE 2 5 Bacterial biotransformation 5.1 Microbial-based biotransformation Due to benefits such as mild reaction conditions and excellent substrate specificity, biotransformation technologies have emerged as a crucial method for the targeted structural alteration of phenolic acids and the creation of high-value derivatives