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83 Hinson and co-workers provided the first evidence for peroxynitrite formation in the liver during APAP hepatotoxicity by demonstrating nitrotyrosine protein adducts

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The phase III study showed that Efmody improved disease control of CAH in the morning normalising the 17OHP throughout the day, whereas on standard treatment, 17OHP rose to excessive levels in the morning but was controlled during the day (Fig