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10.1016/j.neuro.2012.08.011 206 Rahil-KhazenR.BolannB

GLP-1 injections are ideal for adults who struggle with weight loss despite diet and exercise efforts

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My resting heart rate went up a little (enough for my Oura ring to notice) and my perceived effort during exercise was higher during the 3-4 days of highest effectiveness

Collectively, these observations highlight a convergent pathogenic mechanism in NDDs, in which mitochondrial quality control failure, through impaired mitophagy, defective protein import, and ROS-driven dysfunction, links mitochondrial damage, mtDNA-mediated inflammation, and protein aggregation [68,69,70,71,72,73]