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Description

The Tn-seq experiment revealed one gene whose disruption resulted in increased relative survival under conditions of Ssp4 delivery, moaC , and two genes whose disruption resulted in increased relative survival under Ssp6 delivery, xcpW and mucA (FDR 250 bp), and the fragments of interest were adsorbed from the resulting supernatant using an additional 0.4 volumes of bead solution

Zhu J, Cui Y, Zhang J, et al

& Warshaw, R

Obstructive sleep apnea and insight into mechanisms of sympathetic overactivity

This FOXO4-p53 interaction occurs within nuclear PML (promyelocytic leukemia) bodies and is critical for maintaining the viability of senescent cells without it, p53 is free to translocate to mitochondria and trigger intrinsic apoptosis