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This is precisely why it is an interesting research object within studies on skin aging, regeneration and structural support of tissues

At the end of the experiment, the area with new hair covering in the treated skin was measured, and the skin of each animal was harvested for subsequent studies

Pickart estimated lethal dose at approximately 22,500 mg for humans (300-fold above effective doses), with animal LD50 studies in mice showing 8 mg per 25g mouse (320 mg/kg, translating to ~22,400 mg for 154 lb human)

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