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The timetable for recruitment and failures in recruitment, difficulty in forecasting success based on earlier research for particular medications, and total expenditures for such large-scale clinical trials are some of the ongoing difficulties noted

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Ramadi KB, Mohamed YA, Al-Sbiei A et al (2016) Acute systemic exposure to silver-based nanoparticles induces hepatotoxicity and NLRP3-dependent inflammation

Reports the effectiveness of safinamide a reversible MAOB inhibitor that is not a propargylamine derivative in the treatment of Parkinson's disease

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