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Cysteine is toxic to fungi in high concentrations similar to HICA and was included as a comparator

The most frequently reported side effects of GLP-1 medications are gastrointestinal in nature

For SARS-CoV-2 M pro we used our novel tetrapeptide QS1 fluorogenic substrate, that has a lower k cat /K M value (k cat /K M = 859 s 1 M 1 ) in comparison to FRET substrates 22

It's interesting to note that adding nutrients to KBs doesn't always provide full benefits

Apart from improved TQ delivery through the oral route, further development should, therefore, focus on reduced hydrophobicity, thermal instability, and slower degradation of TQ