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ROS-mediated inflammasome activation could explain the increased prevalence of IL-1 found in epilepsy as described above, which may in turn perpetuate cycle of oxidative stress and neuroinflammation

Toxins & Detoxification

For example, injectable pyridoxine solutions may contain aluminum as a trace impurity, and with prolonged use in patients with renal impairment (especially premature neonates with immature kidneys) there is a risk of aluminum accumulation and toxicity

Triglyceride accumulation protects against fatty acid-induced lipotoxicity