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10.3389/fnins.2020.00494 89

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We used the currently approved burden under control number 0938-1314 (CMS-10621), as described in the CY 2024 PFS final rule (88 FR 79444 through 79446) as the baseline to determine the net change in burden

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These effects of IGF-1 LR3 ultimately lead to a reduced insulin requirement by up to 10% in order to maintain blood sugar levels [10, 11, 12]